PleraSan CH is a 1,3/1,6 D beta glucan while oat glucans have a molecular structure of 1,3/1,4 D beta  glucan.  Plerasan CH is an immunomodulator which activates the Langherans cells in the epidermis leading to increased immune activity.  When the Langherans cells are activated cytokines are released which communicate with fibroblasts.  Fibroblast communication results in increased production of chondroblast, collagenoblast, and osteoblast cells.

Oat glucans do not have any immunomodulating properties and do not activate Langherans cells in the epidermis.  PleraSan CH has excellent sensory properties with good physico-chemical stability.  Oat glucans have a tendency to provide off notes resulting in a beer like smell in the cream and on the skin after use.  Yeast glucans have a similar molecular structure to PleraSan CH but have to be carboxymethylated in order to make them soluble which can compromise activity level.  PleraSan CH is a water stable product which does not have to be rendered soluble like the yeast glucans.

Plerasan CH can be pre-dispersed in the water phase, before emulsifying or it can be added after the water phase after emulsification has occurred at a temperature below 60°C.  The recommended usage level for PleraSan CH is between 2% and 10%.