There are pl
enty of products on the market that tout their impact on the functional capacity of the immune system. But how many of them can make the claims of efficacy in multiple clinical studies involving human subjects, the proven safety and consumer acceptance shown by over ten years in consumer products and is isolated from natural, GMO free and allergen free raw materials? Imunoglukan P4H® certainly can.
Imunoglukan P4H® is the trade name for beta-(1,3/1,6)-d-glucans derived from oyster mushroom (Pleurotus ostreatus). This compound also is also scientifically identified by the name “Pleuran”. Identification and processing developments associated with this compound were established by scientists in the 1980’s, patents relating to the compound were filed in the 1990’s and the company Pleuran s.r.o. was established in 2000 to manufacture and develop marketing and sales for this compound. With the launch of the Europe’s first consumer product containing Imunoglukan P4H® in 2001, numerous clinical trials conducted with this compound over a ten year period, and multiple product launches since Imunoglukan P4H®has becomed positioned as the leading immuno-modulation nutraceutical product in Europe.
The mechanism of action for beta-(1,3/1,6)-d-glucans in the human system when ingested can be divided into a few simple steps. As the insoluble molecule of Imunoglukan P4H® passes through the intestines, it will come into contact with small sensors called Peyer’s Patches. These Peyer’s Patches are a collection of lymphoid tissue in the lower intestines that play a part in the immune system by identifying pathogenic organisms and communicating to the rest of the immune system to initiate an appropriate response. Peyer’s Patches also have receptors that identify beta-(1,3/1,6)-d-glucans specifically and will initiate communicate to the rest of the immune system upon identification of this compound. The immune system will then react by initiating an immune response as if it is preparing for potential attack from pathogens.
Clinical trials conducted with healthy human subjects using Imunoglukan P4H® have shown three other important factors. 1. The parameters used to measure efficiency of the immune system are elevated when taking Imunoglukan P4H®, though not beyond levels that are considered normal. 2. The body’s immune system does not develop a dependency on Imunoglukan P4H® to maintain healthy immune function, so when one stops taking Imunoglukan P4H® there is no threat of decreased immune function. And 3. Studies conducted on representative groups including healthy human adults and children as well as domestic animals have shown efficacy and safety for the use of this ingredient across many application ranges.
The clinical studies, along with the presence of numerous consumer products for human and animal nutrition available in the European market for the past decade, provide further evidence to promote the safety and efficacy of this ingredient as a valuable immuno-modulation supplement. Imunoglukan P4H®, when wellness matters.
For information and samples contact sw@aicma.com or visit www.aicma.com.
Vitamin D3 (also known as Cholecolciferol) has generated a lot of great buzz lately in formulation circles, and consumer awareness of this ingredient is increasing exponentially due positive press associated with recent studies involving this ingredient. Research studies from highly respected organizations have theorized this ingredient to have potential impact on a wide variety of health conditions including immunomodulation, various forms of cancer, cardiovascular disease and mortality. Further generating positive press was the US Food and Drug Administration’s amended health claim on calcium and 
osteoporosis, which now includes vitamin d. This new ruling removed many of the historical limitations associated with the claim and specified the ability to clarify the role Vitamin D plays in the body’s ability to absorb calcium. Though this ruling did not became effective until January 1, 2010, manufacturers were permitted to use the claim as early as September 2009.
AIC is proud to be partnered with Fermenta Biotech and Supreem Pharmaceuticals to offer a Vitamin D3 to product developers in the US in a variety forms to meet their specific formulation requirements.
Supreem Pharmaceuticals, India’s most reputed company in the field of Stabilized Vitamins, uses proprietary processing techniques to manufacture Vitamin D3 in cold water dispersable and coated forms for numerous applications.
Fermenta Biotech, India’s first and still the only manufacturer of Vitamin D3, uses over 25 years experience to bring the highest quality, highest purity Vitamin D3 to discerning finished product managers worldwide.
Vitamin D3 and AIC – Many practical applications, one logical source.
For more information and samples contact info@aicma.com or visit www.aicma.com.
Pomegranate extracts have gained a lot of good publicity recently, both as a great source of antioxidants and for other potential benefits such as heart and cancer protection. These benefits are attributed to hydrolysable tannins called Ellagitannins. Those tannins are transformed by the body in Ellagic acid, which is a key to their bioavailability and overall activity. Unlike many other extracts*, Elacyan® 10, produced in France by Tournay Biotechnologies and available exclusively in the US from AIC, does not contain any added Ellagic acid from other cheaper sources but is standardized to the highest Ellagitannins concentration available. Containing the entire spectrum of Pomegranate active phytochemicals, Tournay Biotechnology ensures that Elacyan® 10 exhibits efficiency comparable to what is shown in remarkable scientific studies conducted on Pomegranate.
*http://www.nutraingredients-usa.com/Industry/Study-questions-pomegranate-supplement-standardization
Additional information:
For information and samples contact sw@aicma.com or visit www.aicma.com.
With more than 25% of adults, and more than 17% of children aged 6-19 being obese in the US (and not just overweight), launching healthy products is now more than ever a call of duty for the food industry. As evidenced by the Center for Disease Control and Prevention*, obesity is a major risk factor for cardiovascular disease, certain types of cancer, and type 2 diabetes.
Following numerous positive studies, fibers have gained recent acknowledgement by specialists on their ability to limit food intake and protect from cardiovascular diseases. Most fibers however are not soluble enough, let alone invisible, for use in liquid products such as drinks, smoothies, dairies, dressings… Fibraclear® is a 100% soluble fiber that has no viscosity up to 10% concentration, that gives no off taste, smell or color to your formulation while bringing more than 85% of fibers! Fibraclear® is also stable in a wide range of temperature and pH. This ingredient presents a unique opportunity for beverage and dairy makers to improve their formulation, decrease the glycemic index of their products and help reduce obesity and related diseases prevalence.
Fibraclear®, manufactured by Tournay Biotechnologies, available exclusively through AIC in North America and clearly…a better solution.
* http://www.cdc.gov/obesity/data/trends.html#State
For information and samples contact sw@aicma.com or visit www.aicma.com.
Biocolor and Bionutrition are divisions of South Pole Biogroup, a family of companies focused on the development, manufacturing and marketing of natural products, present in more than 20 countries around the world. The concept of contributing to health through food has not always been as important as it is this day and age. The idea that food can provide well-being beyond nourishment is a reality that has become more and more accepted by consumers and food-related professionals. Since its beginnings, the company’s main focus has been in development of proprietary know-how in key technologies for the stabilization, emulsification and encapsulation of chromaphores and natural ingredients. This continued in-house research has allowed the creation of color formulas that are capable of giving the best technical and more cost-effective natural solution covering, pH and HLB (solubility) range.
Biocolor’s main expertise fields include the beverage industry (alcoholic beverages, soft drinks and powder beverages); the meat industry; snacks (pre-extrusion, slurry and powder cheese colors); margarine; dairy industry (cheese, yoghurt, milk desserts, etc.) powder products; confectionery; pasta and baked products, etc, Biocolor’s customers represent the full spectrum, from small start-up companies to large international retail marketers.
With the objective of satisfying current market demands in the functional and nutraceutical industry, Bionutrition looks towards nature, seeking the raw materials that can deliver health benefits to humans. Via innovative technology, we collect and transform the active ingredients, developing high quality products specifically orientated to dietary supplements and/or nutraceuticals, functional foods and cosmetics.
From manufacturing locations in Chile and the United States, Biocolor and Bionutrition product provide the finest natural colorants and nutritional extracts for food, beverage, nutritional and personal care applications. Biocolors and Bionutrition, fast, simple, reliable and available through AIC in the eastern US.
Additional Information:
South Pole Biogroup – Biocolors / Bionutrition
Southpole Biogroup Biocolor Sample request form
For information and samples contact sw@aicma.com or visit www.aicma.com
Vitatene is a company located in Leon (Spain) belonging to P&R Group. Antibioticos’ 100 years knowledge in fermentation process led in 2003 to the start up of a new dedicated plant to produce carotenoids in an innovative way. Thanks to this strong know-how, Vitatene succeeded in building up a unique technology which enables it to obtain 100% natural carotenoids, formulated in 100% vegetable matrix. Carotenoids are fundamental elements in human and animal health. The essential role of Beta-Carotene and others as the main dietary source of Vitamin A has been known for many years. Carotenoids play an important potential role in human health by acting as biological antioxidants, protecting cells and tissues from damaging effects of free radicals and singlet oxygen. Vitatene’s BETANAT®(Beta-Carotene) and LYCONAT®(Lycopene) derive from a natural fermentative process which involves a fungus, Blakeslea trispora. Vitatene’s LUTENAT®(Lutein) is derived from Marigolds (Tagetes erecta) involving a natural extraction from process. With the increase in the demand for natural products from consumers, Vitatene offers all manufacturers a powerful tool to differentiate their products from those of their competitors. BETANAT®, LYCONAT® and LUTENAT® manfactured by Vitatene, and available exclusively in the US through AIC. The natural answer for superior carotenoids.
Additional Information:
For information and samples contact: sw@aicma.com
American International Chemical Inc. is proud to announce a partnership with Vitatene SA for the promotion of natural carotenoids including Betanat® beta carotene, Lyconat® lycopene and Lutenat® Lutein. Both AIC and Vitatene SA believe that pairing the premier manufacturer of all natural carotenoids, with a sales and marketing organization strongly established in the nutritional, food and personal care markets, will result in positive developments in the months and years to come. With this agreement AIC will assume the sales and marketing responsibilities across all market segments, and looks forward to the promotion and growth of this product line. For literature or samples, please call your local AIC representative, call 800-239-0001, or visit www.aicma.com.
SupplySide West (www.supplysideshow.com/west), the world’s largest event for healthy and innovative ingredients, will be taking place in Las Vegas, NV on November 11th-13th. American International Chemical is proud to be exhibiting along side Davos Life Science, Supreem Pharmaceuticals and Tournay Biotechnologies in booth #19093. As part of this exciting event, AIC is participating in the new Taste of SupplySide sampling program, where you can taste and see the difference that we make with innovative ingredients from these and other supplier partners. AIC also proudly supports the following companies that will also be participating at this exciting event, Graminex LLC (booth #24107), South Pole Biogroup (booth #24015), Vitatene (booth #25036) and Piramal.
The Chicago Section IFT (http://www.chicagoift.org) hosts the largest regional Suppliers’ Night in North America. This exciting event will be taking place at the Donald E. Stephens Convention Center in Rosemont, IL on Wednesday November 11th from noon until 5:30pm. American International Chemical is proud to be participating in the event for the 10th consecutive year. We invite you to stop by booth #942, say hi to Susan, Mike and Yun, and see what innovative ingredients we offer for food, beverage and nutraceutical formulations.
The American Association of Pharmaceutical Scientists (http://www.aapspharmaceutica.com) will be holding their annual meeting and exposition in Los Angeles, CA at the Los Angeles Convention Center on November 8th-12th. As the premier gathering of pharmaceutical scientists from around the world, this year’s meeting will include educational symposiums and a chance to meet representatives from the forefront of every aspect of the pharmaceutical industry. American International Chemical is proud to be attending this show, and representatives from AIC will be present at the booth of BENEO-Palatinit (booth #546) to assist in the promotion of their innovative exipient, galenIQ.
Davos Life Science Pte Ltd is a manufacturer of palm based, solvent free extracted Tocotrienols for nutraceutical, cosmeceutical and pharmaceutical products located in Singapore. In Davos’ state-of-the-art facilities natural tocotrienols from palm oil are isolated and purified. Natural e3® Tocotrienol concentrates from Davos Life Science are successfully used in nutraceutical and cosmeceutical formulations. Pure isomers (alpha-, beta-, gamma- and delta-Tocotrienol, >97%) are used in pharmaceutical applications. Davos also provides Tocotrienol standards for analytical purposes. With the start-up of the Davos Life Science production facilities in Singapore, new standards have been set in the field of natural Tocotrienols. With the world’s largest isolation and purification facilities Davos Life Science is firm their strategic commitment to become the world’s leading production and research organization in the field of natural Tocotrienols. Davos’ team of scientists actively engages in R&D work including clinical trials on applications of natural tocotrienols. Intense research has been performed on Tocotrienol over the past 20 years. This includes numerous investigations into cardiovascular health, cancer, antioxidants, angiogenesis, neurodegeneration, and anti-aging, to name some. The status of Tocotrienol with respect to where the R&D has come from and where its health applications are going show Tocotrienol is beginning to pull itself out of the shadow of its better known Tocopherol cousin. Advances in research with this “Super Vitamin E” have shown the potential for Tocotrienol in supplements, functional foods/drinks, cosmetics/personal care as well as in the pharmaceutical area. Natural e3® Tocotrienol concentrates and powders, manufactured by Davos Life Science, and available in North America from AIC.
Additional Information:
Davos Life Science – Natural e3® Tocotrienols
Davos Tocortienols Matters of the Heart
Davos Tocotrienols The Taste Of Good Health
Davos Tocotrienols Shine Under The Sun
For information and samples contact: sw@aicma.com or visit www.aicma.com.
The multifunctional sugar-free excipient from BENEO-Palatinit is exclusively made from hydrogenated isomaltulose. The direct compressible galenIQTM grades provide excellent compactability. Besides grades for tabletting, galenIQTM comes in different pharmacopeial grades for solid dosage forms like pellets, granules, high boiled lozenges etc.
BENEO-Palatinit will produce galenIQTM under GMP-conditions for pharmaceutical excipients.
galenIQ™ from BENEO-Palatinit – a new definition of a multifunctional excipient
Tableting and more
- Tablets
- Capsule fillings
- High-boiled lozenges
- Granules
- Powder mixtures
- Low boilings
- Pellets
- Pan coatings
For the newest article on galen IQ 981 check out the following link to In-PharmaTechnologist.com:
galenIQ 981 cuts coating time and extends shelf-life, says Beneo Palatinit